Single-blind, randomized, pilot study combining shiatsu and amitriptyline in refractory primary headaches

Une étude scientifique, menée en milieu hospitalier, sur l'efficacité du shiatsu, seul ou en combinaison, avec un médicament, pour les patients souffrants de maux de tête récurrents et publiée dans la revue scientifique Neurological Science (2017) 38:999–1007.

"METHODS:

We tested the efficacy and safety of combining shiatsu and amitriptyline to treat refractory primary headaches in a single-blind, randomized, pilot study. Subjects with a diagnosis of primary headache and who experienced lack of response to ≥2 different prophylactic drugs were randomized in a 1:1:1 ratio to receive shiatsu plus amitriptyline, shiatsu alone, or amitriptyline alone for 3 months. Primary endpoint was the proportion of patients experiencing ≥50%-reduction in headache days. Secondary endpoints were days with headache per month, visual analogue scale, and number of pain killers taken per month.

RESULTS:
Shiatsu (alone or in combination) was superior to amitriptyline in reducing the number of pain killers taken per month (p < 0.05). Seven (19%) subjects reported adverse events, all attributable to amitriptyline, while no side effects were related with shiatsu treatment.

Shiatsu is a safe and potentially useful alternative approach for refractory headache"


Accéder à l'article intégral